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Lovastatin

Lovastatin & Vitamin E

Suppresses absorption of Vitamin E. This medication is commonly used for High Cholesterol

Why Lovastatin affects Vitamin E

Research has found vitamin E supplementation significantly increased the antioxidative capacity of LDL, which was partially abolished by statin therapy. Supplementation with vitamin E should be considered for its antioxidant and anti-inflammatory properties that may help reduce the oxidation of LDL and help protect against cardiovascular diseases.

Clinical Evidence

Shah S, Shiekh Y, Lawrence JA, Ezekwueme F, Alam M, Kunwar S, Gordon DK. A Systematic Review of Effects of Vitamin E on the Cardiovascular System. Cureus. 2021 Jun 12;13(6):e15616. Cynthia M Carlsson et al. Health-related quality of life and long-term therapy with pravastatin and tocopherol (vitamin E) in older adults. Drugs Aging. 2002;19(10):793-805. doi: 10.2165/00002512-200219100-00008. A Palomäki, et al. Effects of lovastatin therapy on susceptibility of LDL to oxidation during alpha-tocopherol supplementation. Arterioscler Thromb Vasc Biol. 1999 Jun;19(6):1541-8. doi: 10.1161/01.atv.19.6.1541

Recommended Replacement

Vitamin E (d-alpha-tocopherol and mixed tocopherols)30IU

Related Health Impacts

  • Neuropathy & Ataxia From Low E

    Vitamin E depletion reduces antioxidant protection of neuronal membranes, leading over time to sensory axonopathy, peripheral neuropathy, ataxia and, occasionally, myopathy.

  • Hemolytic Anemia & Muscle Weakness

    Severe vitamin E deficiency weakens erythrocyte membranes and skeletal muscle fibers, predisposing to hemolytic anemia and proximal muscle weakness.

Supplement Recommendation

Vitamin E (d-alpha tocopherol) 33 mg; mixed tocopherols 6.6mg (providing d-gamma, d-delta and d-beta tocopherols) by Life Extension50 IU

Other Nutrients Affected by Lovastatin

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