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Lovastatin

Lovastatin & Vitamin D3

Suppresses absorption of Vitamin D3. This medication is commonly used for High Cholesterol

Why Lovastatin affects Vitamin D3

Statin therapy can lead to side effects such as statin-associated muscle symptoms (SAMS), rhabdomyolysis myopathy, and myalgia.  Research has demonstrated vitamin D is associated with deficient and insufficient status in patients taking statin drug therapy. It has also found vitamin D to be successful in preventing muscle-related side effects like SAMS.  Supplementation with vitamin D should be considered to avoid a potential deficiency and to help protect against muscle related side effects.

Clinical Evidence

Atalig, Anne Rase MD; DiGiulio, Mary DO. Can vitamin D supplementation decrease risk of statin-induced rhabdomyolysis in patients receiving statin therapy? Evidence-Based Practice: February 2018 - Volume 21 - Issue 2 - p E8-E9. doi: 10.1097/01.EBP.0000541986.24333.6a. Manuela Pennisi et al. Vitamin D Serum Levels in Patients with Statin-Induced Musculoskeletal Pain. Dis Markers. 2019 Mar 25;2019:3549402. doi: 10.1155/2019/3549402. eCollection 2019. Glueck CJ, Budhani SB, Masineni SS, et al. Vitamin D deficiency, myositis-myalgia, and reversible statin intolerance. Curr Med Res Opin 2011;27:1683-90.

Recommended Replacement

Vitamin D3 (Cholecalciferol)500 IU

Supplement Recommendation

Vitamin D3 (Cholcalciferol) (1000 IU) by Nordic Naturals25mcg

Other Nutrients Affected by Lovastatin

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