Suppresses absorption of NAC. This medication is commonly used for High Cholesterol
Statins can lead to elevated liver enzymes, which may increase the risk of liver damage. Studies suggest that liver injury can be associated with statins and potent antioxidants like NAC with its anti-inflammatory action is associated with improved liver circulation, hepatoprotective, and therapeutic in liver conditions and disease.
Abdoli, Narges et al. “Protective Effects of N-acetylcysteine Against the Statins Cytotoxicity in Freshly Isolated Rat Hepatocytes.” Advanced pharmaceutical bulletin vol. 4,3 (2014): 249-54. De Denus S, Spinler SA, Miller K, et al. Statins and liver toxicity: a meta-analysis. Pharmacotherapy. 2004; 24(5):584-591. Alsheikh-Ali AA, Maddukuri PR, Han H, et al. Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer. Journal of the American College of Cardiology 2007;50:409-18. LaRosa JC, Grundy SM, Waters DD, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. New England Journal of Medicine 2005;352:1425?]35.
N-Acetyl Cysteine — 200 mg
N-acetylcysteine is a precursor of cysteine for glutathione synthesis; inadequate NAC availability in high-toxin states can limit hepatic glutathione, increasing vulnerability to oxidative and drug-induced liver injury.