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Hydrochlorothiazide

Nutrients Depleted by Hydrochlorothiazide

Prolonged use of Hydrochlorothiazide can impact 5 essential nutrients. This medication is commonly used for Hypertension.

  • Potassium

    Thiazide diuretics can cause potassium to leave your cells. These medications work by making your kidneys flush out water and sodium, but unfortunately, potassium gets swept along too. This raises the risk of a moderate or severe potassium deficiency, called hypokalemia and potassium supplementation should be considered.

    Replace with Potassium (as citrate and gluconate) (99 mg)

  • CoQ10

    Thiazide diuretics may decrease the effectiveness of enzymes in your heart that rely on CoQ10 for function. This nutrient is essential for cellular energy production. Patients taking these medications might consider CoQ10 supplementation to address potential deficiencies.

    Replace with 50% Ubiquinone and 50% Ubiquinol (50 mg)

  • Folic Acid

    Studies indicate thiazide diuretics may act like folate antagonists, potentially leading to folate deficiency. Research suggests long-term use (over six months) can significantly decrease blood folate levels while increasing homocysteine, a potentially harmful amino acid linked to vascular disease. Folate supplementation should be considered while on thiazide diuretics.

    Replace with Folate (.2mg as L-5-Methylfolate) (0.34 DFE)

  • Zinc

    Thiazide diuretics, a common medication for high blood pressure, can increase how much zinc your body gets rid of through urine. It's advisable to monitor your blood zinc levels while taking these medications and consider zinc supplementation.

    Replace with Zinc (as zinc bisglycinate and (TRAACS™) (12.5mg)

  • Magnesium

    Taking thiazide diuretics long-term can increase magnesium loss. Monitoring magnesium levels and considering supplementation might be necessary when taking thiazide diuretics for an extended period of time.

    Replace with Magnesium Citrate (50 mg)

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