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Hydrochlorothiazide

Hydrochlorothiazide & Zinc

Depletes Zinc. This medication is commonly used for Hypertension

Why Hydrochlorothiazide affects Zinc

Thiazide diuretics, a common medication for high blood pressure, can increase how much zinc your body gets rid of through urine. It's advisable to monitor your blood zinc levels while taking these medications and consider zinc supplementation.

Clinical Evidence

Cohen N, Golik A. Zinc balance and medications commonly used in the management of heart failure. Heart Fail Rev. 2006 Mar;11(1):19-24. Effect of clopamide, a thiazide diuretic, on copper and zinc levels in hypertensive patients. J Am Coll Nutr. 1991 Feb;10(1):34-7. doi: 10.1080/07315724.1991.10718123. A J Reyes, et al. Diuretics and zinc. Afr Med J. 1982 Sep 4;62(11):373-5. M J du Preez et al.

Recommended Replacement

Zinc (as zinc bisglycinate and (TRAACS™)12.5mg

Related Health Impacts

  • Weakened Immune Response

    Zinc depletion compromises innate and adaptive immune responses, leading to lymphopenia, reduced T-cell function and higher susceptibility to infections.

Supplement Recommendation

Zinc Bisglycinate by Pure Encapsulations15 mg

Other Nutrients Affected by Hydrochlorothiazide

Next Steps
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