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Questran

Vision Loss & Dry Eyes

Vitamin A deficiency can damage the surface of the eye in both children and adults, progressing from dry, uncomfortable eyes and night‑vision problems to xerophthalmia and, in severe cases, permanent blindness if it is missed. Regular vitamin A from food and, when appropriate, thoughtfully used supplements can meaningfully reduce this risk; in one large analysis, children in the highest overall intake group had about a 62 percent lower risk of xerophthalmia than those in the lowest group (multivariate relative risk 0.38, 95 percent confidence interval 0.19–0.74). Vitamin A deficiency and xerophthalmia have been documented not just in low‑resource settings but also in at‑risk children and adults in developed countries, so anyone with unexplained dry eyes, night‑vision changes, or corneal findings should have vitamin A status considered and be referred promptly for ophthalmology review to help protect their sight. This medication is commonly used for High Cholesterol.

Sources

Chiu M, Dillon A, Watson S. Vitamin A deficiency and xerophthalmia in children of a developed country. J Paediatr Child Health. 2016 Jul;52(7):699-703. Djunaedi E, Sommer A, Pandji A, Kusdiono, Taylor HR. Impact of Vitamin A Supplementation on Xerophthalmia: A Randomized Controlled Community Trial. Arch Ophthalmol. 1988;106(2):218–222.Chiu M, Watson S. Xerophthalmia and vitamin A deficiency in an autistic child with a restricted diet. BMJ Case Rep. 2015 Oct 5;2015:bcr2015209413. Fawzi WW, Herrera MG, Willett WC, el Amin A, Nestel P, Lipsitz S, Spiegelman D, Mohamed KA. Vitamin A supplementation and dietary vitamin A in relation to the risk of xerophthalmia. Am J Clin Nutr. 1993 Sep;58(3):385-91.

Nutrients Depleted by Questran

Some side effects may be linked to nutrient depletion caused by this medication.

  • Folic AcidDepletion

    Bile acid sequestrants work by binding to cholesterol and bile acids in the intestine, unfortunately, they can also bind to folic acid, hindering its uptake into the bloodstream. For individuals taking bile acid sequestrants, supplementing with folic acid may be advisable to prevent or address potential deficiencies.

  • Vitamin ADepletion

    Bile acid sequestrants work by binding to cholesterol and bile acids in the intestine, unfortunately, they can also bind to fat soluble vitamins like vitamin A, hindering its uptake into the bloodstream. For individuals taking bile acid sequestrants, supplementing with vitamin A may be advisable to prevent or address potential deficiencies.

  • Vitamin D3Depletion

    Bile acid sequestrants work by binding to cholesterol and bile acids in the intestine, unfortunately, they can also bind to fat soluble vitamins like vitamin D3, hindering its uptake into the bloodstream. For individuals taking bile acid sequestrants, supplementing with vitamin D3 may be advisable to prevent or address potential deficiencies.

  • Vitamin EDepletion

    Bile acid sequestrants work by binding to cholesterol and bile acids in the intestine, unfortunately, they can also bind to fat soluble vitamins like vitamin E, hindering its uptake into the bloodstream. For individuals taking bile acid sequestrants, supplementing with vitamin E may be advisable to prevent or address potential deficiencies.

Other Health Impacts of Questran

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