Depletes Vitamin D3. This medication is commonly used for High Cholesterol
Bile acid sequestrants work by binding to cholesterol and bile acids in the intestine, unfortunately, they can also bind to fat soluble vitamins like vitamin D3, hindering its uptake into the bloodstream. For individuals taking bile acid sequestrants, supplementing with vitamin D3 may be advisable to prevent or address potential deficiencies.
Shojania AM, Grewar D. Hypoprothrombinemic hemorrhage due to cholestyramine therapy. CMAJ. 1986;134(6):609-610. M S Matsui et al. Drug-nutrient interaction. Clin Ther. 1982;4(6):423-40. Wakeman M. A Literature Review of the Potential Impact of Medication on Vitamin D Status. Risk Manag Healthc Policy. 2021 Aug 14;14:3357-3381. Robien K, Oppeneer SJ, Kelly JA, Hamilton-Reeves JM. Drug-vitamin D interactions: a systematic review of the literature. Nutr Clin Pract. 2013;28(2):194-208. doi:10.1177/0884533612467824.
Chloecalciferol — 1,000 IU
Vitamin D3 (Cholcalciferol) (1000 IU) by Nordic Naturals — 25mcg