Deficient taurine-mediated modulation of myocardial calcium and mitochondrial function could worsen exercise capacity and symptoms in heart failure, though clear deficiency thresholds are not defined. This medication is commonly used for Pain Management.
Older and recent trials in congestive heart failure report improved left ventricular ejection fraction and functional class with taurine supplementation, implying that higher taurine availability benefits myocardial performance.
Azuma J et al. Double-blind randomized crossover trial of taurine in congestive heart failure. Curr Ther Res Clin Exp. 1983;34:543-557.; Azuma J et al. Usefulness of taurine in chronic congestive heart failure and its prospective application. Jpn Circ J. 1992;56(1):95-99.; Tzang CC et al. Insights into the cardiovascular benefits of taurine. Nutr J. 2024;23(1):995-1008.
Some side effects may be linked to nutrient depletion caused by this medication.
Regular use of non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen may decrease your folic acid (folate) levels. This is because NSAIDs can interfere with how your body processes folate. If you take OTC pain relievers regularly, consider folate supplementation to avoid potential deficiencies.
Recent suggests that damage caused by free radicals in tissues plays a role in stomach ulcers (gastric mucosal lesions) caused by nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen. Based on this, it was investigated whether the amino acid taurine could protect the stomach lining from ibuprofen-induced damage. The study also examined the effects of taurine on the stomach's natural antioxidant defenses, including enzymes like superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX), as well as a molecule called glutathione (GSH). It found that giving taurine orally for three days in a row protected the rats' stomach linings from the ulcers caused by ibuprofen. Additionally, taurine significantly reduced a marker of free radical damage (lipid peroxidation) in the ibuprofen-treated rats.