Suppresses absorption of Taurine. This medication is commonly used for Pain Management
Recent suggests that damage caused by free radicals in tissues plays a role in stomach ulcers (gastric mucosal lesions) caused by nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen. Based on this, it was investigated whether the amino acid taurine could protect the stomach lining from ibuprofen-induced damage. The study also examined the effects of taurine on the stomach's natural antioxidant defenses, including enzymes like superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX), as well as a molecule called glutathione (GSH). It found that giving taurine orally for three days in a row protected the rats' stomach linings from the ulcers caused by ibuprofen. Additionally, taurine significantly reduced a marker of free radical damage (lipid peroxidation) in the ibuprofen-treated rats.
Balasubramanian T, Somasundaram M, Felix AJ. Taurine prevents Ibuprofen-induced gastric mucosal lesions and influences endogenous antioxidant status of stomach in rats. ScientificWorldJournal. 2004 Dec 6;4:1046-54. Walczewska M, Ciszek-Lenda M, Peruń A, Kiecka A, Nazimek K, Kyriakopoulos A, Nagl M, Gottardi W, Marcinkiewicz J. Combined Biological Effects of N-Bromotaurine Analogs and Ibuprofen. Part I: Influence on Inflammatory Properties of Macrophages. Adv Exp Med Biol. 2019;1155:1015-1031. Heidari R, Jamshidzadeh A, Niknahad H, Mardani E, Ommati MM, Azarpira N, Khodaei F, Zarei A, Ayarzadeh M, Mousavi S, Abdoli N, Yeganeh BS, Saeedi A, Najibi A. Effect of taurine on chronic and acute liver injury: Focus on blood and brain ammonia. Toxicol Rep. 2016 Apr 13;3:870-879.
Taurine — 250 mg
Taurine modulates calcium handling, osmoregulation and endothelial function; lower taurine availability has been associated with higher blood pressure and adverse cardiometabolic profiles.
Deficient taurine-mediated modulation of myocardial calcium and mitochondrial function could worsen exercise capacity and symptoms in heart failure, though clear deficiency thresholds are not defined.
Taurine by Pure Encapsulations — 500 mg