Taurine modulates calcium handling, osmoregulation and endothelial function; lower taurine availability has been associated with higher blood pressure and adverse cardiometabolic profiles. This medication is commonly used for Pain Management.
Randomized controlled trials in prehypertensive and cardiovascular patients show that taurine supplementation lowers blood pressure and improves vascular function, suggesting that inadequate taurine can impair cardiovascular regulation under stress.
Sun Q et al. Taurine supplementation lowers blood pressure and improves vascular function in prehypertension: randomized, double-blind, placebo-controlled study. Hypertension. 2016;67(3):541-549.; Li Y et al. Taurine ameliorates blood pressure and vascular function in prehypertension. iScience. 2025;38:00980.; Tzang CC et al. Insights into the cardiovascular benefits of taurine. Nutr J. 2024;23(1):995-1008.
Some side effects may be linked to nutrient depletion caused by this medication.
Regular use of non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen may decrease your folic acid (folate) levels. This is because NSAIDs can interfere with how your body processes folate. If you take OTC pain relievers regularly, consider folate supplementation to avoid potential deficiencies.
Recent suggests that damage caused by free radicals in tissues plays a role in stomach ulcers (gastric mucosal lesions) caused by nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen. Based on this, it was investigated whether the amino acid taurine could protect the stomach lining from ibuprofen-induced damage. The study also examined the effects of taurine on the stomach's natural antioxidant defenses, including enzymes like superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX), as well as a molecule called glutathione (GSH). It found that giving taurine orally for three days in a row protected the rats' stomach linings from the ulcers caused by ibuprofen. Additionally, taurine significantly reduced a marker of free radical damage (lipid peroxidation) in the ibuprofen-treated rats.