Depletes Folic Acid. This medication is commonly used for Stomach Acid
Research suggests that long-term use of H2 blockers and antacids might raise the risk of folic acid deficiency. These medications work by reducing stomach acid, which can also play a role in folic acid absorption. Folic acid is crucial for healthy cell growth and development, and a deficiency can lead to various health problems, especially during pregnancy. Some studies show a potential link between H2 blocker/antacid use and lower folic acid levels. Individuals who take H2 blockers or antacids for extended periods should consider supplementation with folic acid to protect against a deficiency.
Russell RM, Golner BB, Krasinski SD, Sadowski JA, Suter PM, Braun CL. Effect of antacid and H2 receptor antagonists on the intestinal absorption of folic acid. J Lab Clin Med. 1988 Oct;112(4):458-63. Prescott JD, Drake VJ, Stevens JF. Medications and Micronutrients: Identifying Clinically Relevant Interactions and Addressing Nutritional Needs. J Pharm Technol. 2018 Oct;34(5):216-230.
Folate ( .2mg as L-5-Methylfolate) — 0.34 mg DFE