Suppresses absorption of Niacinamide. This medication is commonly used for Pain Management
Acetaminophen, a common pain reliever and fever reducer, is generally safe at recommended doses. However, overdosing can lead to severe oxidative stress, a cellular imbalance that damages the liver and can cause acute liver failure. Niacinamide, a form of vitamin B3, has been shown to be effective in mitigating many conditions caused by oxidative stress. Recent research specifically investigated its ability to protect the liver from acetaminophen damage. The study found that niacinamide offered both preventive (prophylactic) and treatment (therapeutic) benefits.
Mahmoud YI, Mahmoud AA. Role of nicotinamide (vitamin B3) in acetaminophen-induced changes in rat liver: Nicotinamide effect in acetaminophen-damged liver. Exp Toxicol Pathol. 2016 Jun;68(6):345-54.Shi Y, Zhang L, Jiang R, Chen W, Zheng W, Chen L, Tang L, Li L, Li L, Tang W, Wang Y, Yu Y. Protective effects of nicotinamide against acetaminophen-induced acute liver injury. Int Immunopharmacol. 2012 Dec;14(4):530-7.
Niacinamide — 100 mg
Niacinamide by Pure Encapsulations — 100 mg