Prevalite

Prevalite is a medication that is used to lower high levels of cholesterol in the blood. It belongs to a class of drugs known as bile acid sequestrants, and works by binding to bile acids in the intestine, leading to decreased absorption of cholesterol. Prevalite is typically prescribed to help lower cholesterol levels in individuals with high cholesterol or those at risk for heart disease.

Overview Why It Happens Clinical Evidence Replacement Supplement Other Nutrients

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Prevalite

Prevalite & Vitamin E

Depletes Vitamin E. This medication is commonly used for High Cholesterol

Why Prevalite affects Vitamin E

Bile acid sequestrants work by binding to cholesterol and bile acids in the intestine, unfortunately, they can also bind to fat soluble vitamins like vitamin E, hindering its uptake into the bloodstream. For individuals taking bile acid sequestrants, supplementing with vitamin E may be advisable to prevent or address potential deficiencies.

Clinical Evidence

Threlkeld DS, ed. Cardiovascular Drugs, Antihyperlipidemic Agents, Bile Acid Sequestrants. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1999, 171L.M S Matsui et al. Drug-nutrient interaction. Clin Ther. 1982;4(6):423-40.Werbach MR. Foundations of Nutritional Medicine. Tarzana, CA: Third Line Press, 1997, 224.

Recommended Replacement

Vitamin E (d-alpha tocopherol with mixed tocopherols) — 30 IU

Supplement Recommendation

Vitamin E (d-alpha tocopherol) 33 mg; mixed tocopherols 6.6mg (providing d-gamma, d-delta and d-beta tocopherols) by Life Extension — 50 IU

Other Nutrients Affected by Prevalite

Vitamin K — Depletion
Vitamin A — Depletion
Vitamin D3 — Depletion
Folic Acid — Depletion

Next Steps

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