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Prednisone

Prednisone & Potassium

Depletes Potassium. This medication is commonly used for Inflammation

Why Prednisone affects Potassium

Maintaining healthy potassium levels is important when taking corticosteroids. These medications can increase the amount of potassium the body loses through urine. Potassium is a vital mineral that helps muscles and nerves function properly. While short-term use of corticosteroids might not cause significant problems, studies suggest that with prolonged treatment, the body's ability to maintain proper potassium balance (homeostasis) can be affected.

Clinical Evidence

Pariury H, Willhoite J, Michlitsch J, Agrawal A. Potassium supplementation mitigates corticosteroid-induced neuropsychiatric effects in pediatric oncology patients. Pediatr Hematol Oncol. 2019 Oct;36(7):445-450. Shenfield GM, Knowles GK, Thomas N, Paterson JW. Potassium supplements in patients treated with corticosteroids. Br J Dis Chest. 1975 Jul;69:171-6. Mohn ES, Kern HJ, Saltzman E, Mitmesser SH, McKay DL. Evidence of Drug-Nutrient Interactions with Chronic Use of Commonly Prescribed Medications: An Update. Pharmaceutics. 2018 Mar 20;10(1):36. Dr. Mathew George, et al. Effect of Corticosteroids on Serum Potassium Levels in Patients with Obstructive Airway Disorders. International Journal of Health Sciences & Research 430. Vol.7; Issue: 4; April 2017.

Recommended Replacement

Potassium (as gluconate)99 mg

Related Health Impacts

  • Constipation & Rhythm Disturbances

    Low potassium slows smooth muscle activity in the gut, leading to constipation, and destabilizes cardiac repolarization, increasing risk of palpitations and dangerous arrhythmias in susceptible patients.

Supplement Recommendation

Potassium (as gluconate) by Pure Encapsulations200mg

Other Nutrients Affected by Prednisone

Next Steps
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