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Plendil

Plendil & Potassium

Depletes Potassium. This medication is commonly used for Hypertension

Why Plendil affects Potassium

An increased excretion of potassium can occur in people taking calcium channel blocker drugs like felodipine. Supplementation may need to be considered if blood levels of potassium are low.

Clinical Evidence

Hulthen UL, Katzman PL. Renal effects of acute and long-term treatment with felodipine in essential hypertension. J Hypertens 1988;6:231–7. Werbach MR. Foundations of Nutritional Medicine. Tarzana, CA: Third Line Press, Inc., 1997, 208. Freed MI, Rastegar A, Bia MJ. Effects of calcium channel blockers on potassium homeostasis. Yale J Biol Med. 1991 Mar-Apr;64(2):177-86.

Recommended Replacement

Potassium (as citrate and gluconate)99 mg

Related Health Impacts

  • Irregular Heart Rhythm

    Potassium deficiency can destabilize the heart’s electrical system, so hypokalemia is a well‑known trigger for cardiac arrhythmias and can present with palpitations, “skipped beats,” or more dangerous rhythm disturbances even before other symptoms are obvious. As serum potassium drops, characteristic ECG changes (flattened or inverted T waves, ST‑segment depression, prominent U waves, and QT‑interval prolongation) reflect impaired repolarization, which can progress to premature ventricular contractions, atrial fibrillation, ventricular tachycardia, torsade de pointes, or even ventricular fibrillation and cardiac arrest in severe cases. Observational data show that hypokalemia and even low‑normal potassium levels increase the risk of ventricular arrhythmias and sudden cardiac death in people with underlying heart disease, highlighting the importance of monitoring and promptly correcting potassium deficits in hospitalized and high‑risk patients.

Supplement Recommendation

Potassium (as gluconate) by Pure Encapsulations200mg

Other Nutrients Affected by Plendil

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