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Painaid

Painaid & Zinc

Depletes Zinc. This medication is commonly used for Pain Management

Why Painaid affects Zinc

Studies indicate that medications like aspirin can increase zinc loss through urine. Zinc plays a vital role in wound healing, protein synthesis, cell reproduction, immunity, and vision. If you take aspirin regularly, consider monitoring zinc levels and supplementation may be beneficial to prevent a deficiency.

Clinical Evidence

Babu SSN, Singla S, Jena G. Role of Combination Treatment of Aspirin and Zinc in DMH-DSS-induced Colon Inflammation, Oxidative Stress and Tumour Progression in Male BALB/c Mice. Biol Trace Elem Res. 2023 Mar;201(3):1327-1343. Christudoss P, Selvakumar R, Pulimood AB, Fleming JJ, Mathew G. Protective role of aspirin, vitamin C, and zinc and their effects on zinc status in the DMH-induced colon carcinoma model. Asian Pac J Cancer Prev. 2013;14(8):4627-34.

Recommended Replacement

Zinc Bisglycinate12.5 mg

Related Health Impacts

  • Age-Related Vision Loss

    Low zinc status has been linked to a higher risk and faster progression of age-related macular degeneration (AMD), in part because zinc is concentrated in the retina and supports antioxidant defenses there. In the landmark AREDS trial, a supplement formula containing zinc (80 mg as zinc oxide), along with antioxidants, reduced the risk of progression to advanced AMD by about 25% in people with intermediate disease or advanced disease in one eye over roughly 5 years. Other research has shown that inadequate zinc intake is more common in older adults with AMD, reinforcing the idea that maintaining healthy zinc levels may be an important, and often overlooked, strategy for preserving macular health with age.

  • Brain Fog & Neurological Effects

    Zinc deficiency has been associated with a range of neurological and behavioral changes, including increased irritability, poor attention, and slowed cognitive processing. In children, low zinc status has been linked to poorer performance on tests of attention, memory, and school achievement, and some trials have found that zinc supplementation can modestly improve certain cognitive scores, especially in previously deficient populations. Clinically, even mild zinc deficiency may present with subtle symptoms such as mood changes, reduced stress tolerance, and “brain fog,” which can easily be overlooked but may improve when zinc status is corrected.

Supplement Recommendation

Zinc Bisglycinate by Pure Encapsulations15 mg

Other Nutrients Affected by Painaid

Next Steps
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