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Felodipine

Felodipine & Calcium

Depletes Calcium. This medication is commonly used for Hypertension

Why Felodipine affects Calcium

Studies suggest that Felodipine, a type of calcium channel blocker (CCB), may increase the excretion of calcium in the urine. While the long-term effects on bone health are unclear, some healthcare professionals suggest calcium supplementation for patients taking felodipine, especially those at higher risk of osteoporosis.

Clinical Evidence

Schmitz A. Acute renal effects of oral felodipine in normal man. Eur J Clin Pharmacol. 1987;32(1):17-22. doi: 10.1007/BF00609952. PMID: 3582465. Hulthén UL, Katzman PL. Renal effects of acute and long-term treatment with felodipine in essential hypertension. J Hypertens. 1988 Mar;6(3):231-7.

Recommended Replacement

Calcium Citrate50 mg

Related Health Impacts

  • High Blood Pressure & Heart Risk

    Across the lifespan, chronically low calcium intake has been linked to higher blood pressure, in part because calcium plays a key role in vascular smooth‑muscle contraction, sodium handling, and endothelial function. Large epidemiologic studies and randomized trials suggest that individuals with higher dietary calcium intake tend to have modestly lower systolic and diastolic blood pressures and may experience a small but meaningful reduction in risk of stroke and other cardiovascular events. The practical takeaway is that maintaining adequate daily calcium, alongside blood pressure control, exercise, and a heart‑healthy diet, may be an underutilized strategy to support vascular health and reduce long‑term cardiovascular risk.

  • Weak Bones & Fractures

    Low or depleted magnesium levels are associated with a higher risk of osteoporosis and fractures, with studies linking magnesium deficiency to a 25–35% increased risk of hip, wrist, and spine fractures in some populations. Magnesium deficiency impairs bone mineralization and vitamin D activation, compounding skeletal weakness by disrupting osteoblast function and calcium balance. This is particularly concerning for older adults or those with additional risk factors, where monitoring magnesium status and considering supplementation may help mitigate bone loss.

Supplement Recommendation

Calcium Citrate by Solaray200mg

Other Nutrients Affected by Felodipine

Get Support

Prolonged use of Felodipine can leave gaps in your nutrition. A targeted supplement can help restore balance while you continue treatment.

Amlodipine Support — Felodipine Support Formula

Amlodipine Support

A bespoke formula designed to replenish the nutrients depleted by Felodipine.

Once Daily Capsule · Rx Not Required

Learn More
Next Steps
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