Colestipol

Colestipol is a medication used to lower cholesterol in the blood. It works by binding to bile acids in the intestines, preventing them from being reabsorbed into the body. This causes the liver to produce more bile acids from cholesterol, which in turn lowers the levels of cholesterol in the blood. Colestipol is often prescribed to individuals with high cholesterol levels who are at risk for heart disease.

Overview Why It Happens Clinical Evidence Replacement Other Nutrients

Next Steps

Save this report and share it with your healthcare provider or a family member

Ask our expert AI assistant additional questions related to Colestipol.

On this page

Colestipol

Colestipol & Vitamin K

Depletes Vitamin K. This medication is commonly used for High Cholesterol

Why Colestipol affects Vitamin K

Bile acid sequestrants work by binding to cholesterol and bile acids in the intestine, unfortunately, they can also bind to fat soluble vitamins like vitamin K, hindering its uptake into the bloodstream. For individuals taking bile acid sequestrants, supplementing with vitamin K may be advisable to prevent or address potential deficiencies.

Clinical Evidence

A M Shojania et al. Hypoprothrombinemic hemorrhage due to cholestyramine therapy. CMAJ. 1986 Mar 15;134(6):609-10. M S Matsui et al. Drug-nutrient interaction. Clin Ther. 1982;4(6):423-40.K Vroonhof et al. Vitamin K deficiency and bleeding after long-term use of cholestyramine. Neth J Med. 2003 Jan;61(1):19-21.

Recommended Replacement

Vitamin K1 — 500 mcg

Other Nutrients Affected by Colestipol

Vitamin D3 — Depletion
Vitamin E — Depletion
Vitamin A — Depletion
Folic Acid — Depletion

Next Steps

Save this report and share it with your healthcare provider or a family member

Ask our expert AI assistant additional questions related to Colestipol.