Vitamin A and beta carotene are essential for maintaining the integrity of the cornea and the light-sensing pigments in the retina, so deficiency greatly increases the risk of night blindness and other ocular pathologies. In vitamin A deficient regions, hundreds of thousands of children each year develop xerophthalmia, ranging from conjunctival and corneal dryness to corneal ulceration and keratomalacia, which can progress to irreversible blindness if not corrected. Even subclinical deficiency can impair dark adaptation and increase susceptibility to eye infections, making adequate vitamin A and carotenoid intake a critical foundation for long-term visual health. This medication is commonly used for High Cholesterol.
Haskell MJ, Pandey P, Graham JM, Peerson JM, Shrestha RK, Brown KH. Recovery from impaired dark adaptation in nightblind pregnant Nepali women who receive small daily doses of vitamin A as amaranth leaves, carrots, goat liver, vitamin A-fortified rice, or retinyl palmitate. Am J Clin Nutr. 2005 Feb;81(2):461-71. Ten Hulzen RD, Wagner IV, Decastro PY, Sullivan JP. Visual field decline and restoration following vitamin A therapy for vitamin A deficiency. Am J Ophthalmol Case Rep. 2022 Mar 5;26:101471. Smith, Janine M.D.; Steinemann, Thomas L. M.D.. Vitamin A Deficiency and the Eye. International Ophthalmology Clinics 40(4):p 83-91, Fall 2000. Hu Y, Chen Y, Moiseyev G, Takahashi Y, Mott R, Ma JX. Comparison of ocular pathologies in vitamin A-deficient mice and RPE65 gene knockout mice. Invest Ophthalmol Vis Sci. 2011 Jul 25;52(8):5507-14.
Some side effects may be linked to nutrient depletion caused by this medication.
Bile acid sequestrants work by binding to cholesterol and bile acids in the intestine, unfortunately, they can also bind to folic acid, hindering its uptake into the bloodstream. For individuals taking bile acid sequestrants, supplementing with folic acid may be advisable to prevent or address potential deficiencies.
Bile acid sequestrants work by binding to cholesterol and bile acids in the intestine, unfortunately, they can also bind to fat soluble vitamins like vitamin A, hindering its uptake into the bloodstream. For individuals taking bile acid sequestrants, supplementing with vitamin A may be advisable to prevent or address potential deficiencies.
Bile acid sequestrants work by binding to cholesterol and bile acids in the intestine, unfortunately, they can also bind to fat soluble vitamins like vitamin E, hindering its uptake into the bloodstream. For individuals taking bile acid sequestrants, supplementing with vitamin E may be advisable to prevent or address potential deficiencies.
Bile acid sequestrants work by binding to cholesterol and bile acids in the intestine, unfortunately, they can also bind to fat soluble vitamins like vitamin D3, hindering its uptake into the bloodstream. For individuals taking bile acid sequestrants, supplementing with vitamin D3 may be advisable to prevent or address potential deficiencies.