Depletes Zinc. This medication is commonly used for Pain Management
Studies indicate that medications like aspirin can increase zinc loss through urine. Zinc plays a vital role in wound healing, protein synthesis, cell reproduction, immunity, and vision. If you take aspirin regularly, consider monitoring zinc levels and supplementation may be beneficial to prevent a deficiency.
Babu SSN, Singla S, Jena G. Role of Combination Treatment of Aspirin and Zinc in DMH-DSS-induced Colon Inflammation, Oxidative Stress and Tumour Progression in Male BALB/c Mice. Biol Trace Elem Res. 2023 Mar;201(3):1327-1343. Christudoss P, Selvakumar R, Pulimood AB, Fleming JJ, Mathew G. Protective role of aspirin, vitamin C, and zinc and their effects on zinc status in the DMH-induced colon carcinoma model. Asian Pac J Cancer Prev. 2013;14(8):4627-34.
Zinc Bisglycinate — 12.5 mg
Low zinc status has been linked to a higher risk and faster progression of age-related macular degeneration (AMD), in part because zinc is concentrated in the retina and supports antioxidant defenses there. In the landmark AREDS trial, a supplement formula containing zinc (80 mg as zinc oxide), along with antioxidants, reduced the risk of progression to advanced AMD by about 25% in people with intermediate disease or advanced disease in one eye over roughly 5 years. Other research has shown that inadequate zinc intake is more common in older adults with AMD, reinforcing the idea that maintaining healthy zinc levels may be an important, and often overlooked, strategy for preserving macular health with age.
Zinc deficiency has been associated with a range of neurological and behavioral changes, including increased irritability, poor attention, and slowed cognitive processing. In children, low zinc status has been linked to poorer performance on tests of attention, memory, and school achievement, and some trials have found that zinc supplementation can modestly improve certain cognitive scores, especially in previously deficient populations. Clinically, even mild zinc deficiency may present with subtle symptoms such as mood changes, reduced stress tolerance, and “brain fog,” which can easily be overlooked but may improve when zinc status is corrected.
Closely linked to reproductive and hormonal problems in both men and women, zinc deficiency can contribute to hypogonadism, low testosterone, reduced sperm count, and menstrual irregularities. In men, low zinc status has been associated with decreased serum testosterone, reduced sperm density and motility, and poorer overall semen quality, while zinc repletion in deficient individuals has been shown to improve some of these parameters. In women, inadequate zinc intake is tied to more frequent cycle disturbances, dysmenorrhea, and potential impacts on ovulation and fertility, underscoring zinc’s important role in healthy hormonal balance and reproductive function.
Zinc Bisglycinate by Pure Encapsulations — 15 mg