Prolonged use of Valsartan + Amlodipine can impact 2 essential nutrients. This medication is commonly used for Hypertension.
This drug is a comprehensive combination of a calcium channel blocker and angiotensin receptor blocker. Calcium channel blockers (CCBs), particularly nifedipine, can cause gum tissue overgrowth (gingival hyperplasia) in both men and women. Studies suggest a dose-dependent link with CCBs potentially doubling the risk. Studies also confirm a link between CCB use (like amlodipine and nifedipine) and gingival hyperplasia, even beyond factors like poor hygiene. Research suggests impaired folate uptake in gum tissue might be another key contributor. Supplementation with folate to help protect against CCB-induced hyperplasia may be beneficial.
Replace with Folate (.2mg as L-5-Methylfolate) (0.34 DFE)
This drug is a comprehensive combination of a calcium channel blocker and angiotensin receptor blocker. Studies have shown that treatment with medications like Angiotensin Receptor Blockers (ARBs) can lead to zincuria, which is increased urinary excretion of zinc. This increased excretion may potentially lead to zinc deficiency in some individuals and therefore supplementation should be considered.
Replace with Zinc (as zinc bisglycinate and (TRAACS™) (12.5 mg)