Torsemide & Thiamine Vitamin B1
Depletes Thiamine Vitamin B1. This medication is commonly used for Hypertension
Why Torsemide affects Thiamine Vitamin B1
Thiamine (vitamin B1) deficiency in patients with cardiovascular disease might be linked to two factors associated with loop diuretics: increased urine output, and cellular uptake inhibition. Loop diuretics can significantly increase urine volume and urinary flow rate, potentially leading to increased thiamine excretion through urine. Emerging evidence suggests loop diuretics may directly inhibit the cellular uptake of thiamine, further contributing to deficiency. Thiamine supplementation during loop diuretic therapy should therefore be considered.
Clinical Evidence
Zenuk C, et al. Thiamine deficiency in congestive heart failure patients receiving long term furosemide therapy. Can J Clin Pharmacol. 2003 Winter;10(4):184-8. Katta et al. Does Long-Term Furosamide Therapy cause thiamne deficiency? Am J Med 2016 Jul; 129 (7): 753. Seligmann H, Halkin H, Rauchfleisch S, et al. Thiamine deficiency in patients with congestive heart failure receiving long-term furosemide therapy: a pilot study. Am J Med . 1991;91(2):151-155.
Recommended Replacement
Vitamin B1 Thiamin HCl — 10 mg
Get Support
Prolonged use of Torsemide can leave gaps in your nutrition. A targeted supplement can help restore balance while you continue treatment.
Furosemide Support™
A bespoke formula designed to replenish the nutrients depleted by Torsemide.
Once Daily Capsule · Rx Not Required
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