In both children and adults, chronically low calcium intake can undermine the mineralization of teeth and supporting bone, contributing to enamel hypoplasia, root resorption, and loss of alveolar bone that stabilizes the teeth. Epidemiologic studies have linked lower dietary calcium and dairy intake with higher rates of periodontitis, tooth mobility, and tooth loss, especially in older adults and postmenopausal women. The encouraging piece is that maintaining adequate calcium (alongside vitamin D and good oral hygiene) appears to support healthier periodontal bone and may reduce the risk of dental defects and tooth loss over time. This medication is commonly used for Pain Management.
Nishida M, Grossi SG, Dunford RG, Ho AW, Trevisan M, Genco RJ. Calcium and the risk for periodontal disease. J Periodontol. 2000 Jul;71(7):1057-66. Nascimento GG, Leite FRM, Gonzalez-Chica DA, Peres KG, Peres MA. Dietary vitamin D and calcium and periodontitis: A population-based study. Front Nutr. 2022 Dec 22;9:1016763. Miley DD, Garcia MN, Hildebolt CF, Shannon WD, Couture RA, Anderson Spearie CL, Dixon DA, Langenwalter EM, Mueller C, Civitelli R. Cross-sectional study of vitamin D and calcium supplementation effects on chronic periodontitis. J Periodontol. 2009 Sep;80(9):1433-9. Nishida, M., Grossi, S.G., Dunford, R.G., Ho, A.W., Trevisan, M. and Genco, R.J. (2000), Calcium and the Risk For Periodontal Disease. Journal of Periodontology, 71: 1057-1066.
Some side effects may be linked to nutrient depletion caused by this medication.
Indomethacin, a medication commonly used to treat inflammation and pain, can decrease the absorption of vitamin C. Vitamin C plays a vital role in immune function and the body's antioxidant defenses. To counteract this effect and maintain a healthy immune system and antioxidant capacity, vitamin C supplementation is recommended for individuals taking Indomethacin.
Studies suggest that indomethacin, a type of nonsteroidal anti-inflammatory drug (NSAID), might decrease calcium levels in the body. To prevent potential calcium deficiency, supplementation should be considered for individuals taking indomethacin on a long-term basis.