Spironolactone

Spironolactone is a medication that is primarily used to treat high blood pressure and fluid retention (edema) in conditions such as congestive heart failure, liver cirrhosis, and kidney disease. It is a potassium-sparing diuretic, which means that it helps the body get rid of excess fluid and sodium while retaining potassium. In addition to its diuretic properties, spironolactone is also used to treat hormonal acne in women, hirsutism (excessive hair growth), and female pattern hair loss.

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Spironolactone

Nutrients Depleted by Spironolactone

Prolonged use of Spironolactone can impact 1 essential nutrient. This medication is commonly used for Hypertension.

Folic Acid
Studies indicate that diuretics including potassium-sparing, can act as folate antagonists, potentially leading to a deficiency. This occurs because some diuretics inhibit the enzyme responsible for utilizing folate (folic acid) in the body. Research suggests a link between long-term diuretic use (over six months) and decreased blood folate levels while also showing a significant increase in damaging homocysteine levels. Folate supplementation during potassium-sparing diuretic therapy should therefore be considered.
Replace with Folate (.2mg as L-5-Methylfolate) (0.34 DFE)

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