Depletes Magnesium. This medication is commonly used for Hypertension
Loop diuretics can disrupt the kidneys' ability to reabsorb magnesium, leading to increased excretion of this essential mineral through urine. This potential depletion necessitates monitoring magnesium levels, especially in individuals undergoing long-term loop diuretic therapy. Supplementing with magnesium may be beneficial in such cases to help protect against a deficiency.
Cohen N, et al. Metabolic and clinical effects of oral magnesium supplementation in furosemide-treated patients with severe congestive heart failure. Clin Cardiol. 2000 Jun;23(6):433-6. Iezhitsa IN, et al. Comparative study of the efficacy of potassium magnesium L-, D- and DL-aspartate stereoisomers in overcoming digoxin- and furosemide-induced potassium and magnesium depletions. Magnes Res. 2004 Dec;17(4):276-92. Efstratiadis G, et al. Hypomagnesemia and cardiovascular system. Hippokratia. 2006 Oct;10(4):147-52. Quamme GA. Renal magnesium handling: new insights in understanding old problems. Kidney Int . 1997;52(5):1180-1195.
Magnesium Citrate — 50 mg
Low or depleted magnesium levels are associated with a higher likelihood of several cardiovascular problems, including arrhythmias, where people with low magnesium have been shown to have 2–4 times higher odds of these rhythm disturbances compared with those with normal levels. Low magnesium is also linked to worsening coronary artery disease, progression of heart failure, and development or aggravation of hypertension, driven by disrupted cardiac electrical stability, vascular function, and electrolyte balance. Even mild magnesium depletion may contribute to higher blood pressure over time, adding to the overall cardiovascular burden, especially in individuals with existing heart disease or multiple risk factors.
Magnesium (as Magnesium Citrate) by Pure Encapsulations — 150 mg