Create an account to receive alerts on new research
SaveShareAsk AI
Milk of Magnesia
Depletes
Prolonged use of Milk of Magnesia can impact 4 essential nutrients.
Folic Acid
Research suggests that long-term use of H2 blockers and antacids might raise the risk of folic acid deficiency. These medications work by reducing stomach acid, which can also play a role in folic acid absorption. Folic acid is crucial for healthy cell growth and development, and a deficiency can lead to various health problems, especially during pregnancy. Some studies show a potential link between H2 blocker/antacid use and lower folic acid levels. Individuals who take H2 blockers or antacids for extended periods should consider supplementation with folic acid to protect against a deficiency.
Replace with Folate (.2mg as L-5-Methylfolate) (0.34 mg DFE)
Research: Russell RM, Golner BB, Krasinski SD, Sadowski JA, Suter PM, Braun CL. Effect of antacid and H2 receptor antagonists on the...
Also Benefits From:
Vitamin B 6 (as pyridoxal 5'-phosphate)
Vitamin B-6 helps regulate immune responses in the gut, potentially reducing inflammation that can contribute to digestive issues. One of the concerns of Gastro Esophageal Reflux Disorder ( GERD) or Gastric Reflux is the progression to more complicated condition such as Barrett’s Esophagus (BE) or even Esophageal adenocarcinoma (EAC) by increased inflammation. While treatment of GERD with Proton Pump Inhibitors or H2 Antagonists may help treat or reduce risk, a study on the effects of B Vitamins found that Vitamin B6 intake was significantly inversely related to the risks of all three lesions of GERD, BE or EAC. Patients concerned with these conditions should consider Vitamin B6 supplementation.
Research: Sharp L, Carsin AE, Cantwell MM, Anderson LA, Murray LJ; FINBAR Study Group. Intakes of dietary folate and other B vitamins...
Vitamin B6 (as pyridoxine hydrochloride)
Vitamin B-6 helps regulate immune responses in the gut, potentially reducing inflammation that can contribute to digestive issues. One of the concerns of Gastro Esophageal Reflux Disorder ( GERD) or Gastric Reflux is the progression to more complicated condition such as Barrett’s Esophagus (BE) or even Esophageal adenocarcinoma (EAC) by increased inflammation. While treatment of GERD with Proton Pump Inhibitors or H2 Antagonists may help treat or reduce risk, a study on the effects of B Vitamins found that Vitamin B6 intake was significantly inversely related to the risks of all three lesions of GERD, BE or EAC. Patients concerned with these conditions should consider Vitamin B6 supplementation.
Research: Sharp L, Carsin AE, Cantwell MM, Anderson LA, Murray LJ; FINBAR Study Group. Intakes of dietary folate and other B vitamins...
Vitamin K2 (Menaquinone-7)
Research demonstrates that vitamin D3 and K2 can provide greater benefit together. Vitamin D3 and K2 help move calcium into your bones, where it's most beneficial. This prevents calcium buildup in your arteries and blood vessels. Their combined action can boost bone health, promote cardiovascular health, and combat inflammation. Both vitamins show promise in regulating inflammation, a key factor in many health concerns. By collaborating, vitamin D3 and K2 offer a broader spectrum of benefits, potentially protecting against serious illnesses and promoting overall well-being.
Research: Kuang X, Liu C, Guo X, Li K, Deng Q, Li D. The combination effect of vitamin K and vitamin D on human bone quality: a...
Health Impact
Milk of Magnesia-induced nutrient depletion can lead to a range of health problems
High Homocysteine & Vascular Risk
Meta-analyses of randomized trials show that folic acid supplementation lowers homocysteine and modestly reduces stroke and overall cardiovascular disease risk in some populations, especially where baseline folate status is low, highlighting the adverse vascular profile of folate deficiency.
Research: Li Y et al. Folic acid supplementation and the risk of cardiovascular diseases: a meta-analysis of randomized controlled...
Folate-Related Megaloblastic Anemia
Hematology and nutrition reviews describe folate deficiency as a classic cause of megaloblastic anemia and mucosal abnormalities, frequently exacerbated by medications that antagonize folate metabolism.
Research: O’Leary F, Samman S. Vitamin B12 in health and disease. Nutrients. 2010;2(3):299-316. (discussion of folate and B12 in...
Side Effects
Common side effects of Milk of Magnesia, some of which may be related to nutrient depletion
Review
Some possible side effects of Milk of Magnesia (magnesium hydroxide) include:
- Diarrhea or upset stomach
- Nausea or vomiting
- Loss of appetite
- Dizziness or lightheadedness
- Muscle weakness or cramps
- Rash or itching
- Swelling of the face, lips, or throat (sign of an allergic reaction)
It is important to consult a healthcare provider if any of these side effects persist or worsen. Additionally, long-term or excessive use of Milk of Magnesia may lead to imbalanced electrolytes, kidney problems, or other serious complications.
- Diarrhea or upset stomach
- Nausea or vomiting
- Loss of appetite
- Dizziness or lightheadedness
- Muscle weakness or cramps
- Rash or itching
- Swelling of the face, lips, or throat (sign of an allergic reaction)
It is important to consult a healthcare provider if any of these side effects persist or worsen. Additionally, long-term or excessive use of Milk of Magnesia may lead to imbalanced electrolytes, kidney problems, or other serious complications.
Get Support
We've curated a list of vetted, recommended individual nutrient third-party supplements.
Shop Third-Party Supplements
Folate
by Pure Encapsulations
Pure Encapsulations' Folic Acid supplement provides a high-quality, bioavailable form of folic acid to support healthy fetal development, cardiovascular health, and overall cellular function.
Strength: 800 mcg
Buy now
Folate
Expert Research
Recommended
Recommended
Antidote is a free resource, supported among other sources by affiliate commissions for purchases made through links on our site. Read full disclaimer
Next Steps
Save this report and share it with your healthcare provider or a family member
Ask our expert AI assistant additional questions related to Milk of Magnesia.