Suppresses absorption of Vitamin E. This medication is commonly used for High Cholesterol
Fenofibrate has been shown in studies to increase the toxic effect of ultraviolet (UV) radiation that may lead to side effects such as hives, itching, and skin rash. Taking vitamin E before UV exposure is found in research to significantly help block UV-fenofibrate effects on the skin. Vitamin E supplementation should be considered when taking this drug therapy.
Eberlein-Konig B, Placzek M, Przybilla B. Phototoxic lysis of erythrocytes from humans is reduced after oral intake of ascorbic acid and d-alpha-tocopherol. Photodermatol Photoimmunol Photomed 1997;13:173-7.
Vitamin E (d-alpha-tocopherol and mixed tocopherols) — 30 IU
In both children and adults, vitamin E deficiency can contribute to retinopathy and visual impairment because α‑tocopherol serves as a key fat‑soluble antioxidant that protects photoreceptor cells and retinal membranes from cumulative oxidative damage. Clinical reports describe patients with prolonged low vitamin E status developing pigmentary retinopathy, reduced visual acuity, and abnormal electroretinograms, sometimes alongside peripheral neuropathy, which can improve partially when deficiency is identified and corrected. These neurosensory changes appear more frequently in settings of fat malabsorption or genetic disorders affecting vitamin E transport, highlighting the importance of monitoring vitamin E status in at‑risk groups with otherwise unexplained visual decline.
Vitamin E (d-alpha tocopherol) 33 mg; mixed tocopherols 6.6mg (providing d-gamma, d-delta and d-beta tocopherols) by Life Extension — 50 IU