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Leena

Leena & Magnesium

Depletes Magnesium. This medication is commonly used for Contraception

Why Leena affects Magnesium

Research suggests a potential decrease in magnesium levels in women using Oral Contraceptives (OCs). Studies have shown that women taking OCs have significantly lower serum magnesium compared to those not using them. Interestingly, the type of pill or duration of use doesn't seem to influence the degree of magnesium depletion. The observed decrease in magnesium with OC use might be associated with an increased risk of blood clots. Supplementation with magnesium should be considered during oral contraceptives use.

Clinical Evidence

Blum M, Kitai E, Ariel Y, Schnierer M, Bograd H. [Oral contraceptive lowers serum magnesium]. Harefuah. 1991 Nov 15;121(10):363-4. Hebrew. PMID: 1752550.Shikh EV, Makhova AA, Chemeris AV, Tormyshov IA. [Iatrogenic deficits of micronutrients]. Vopr Pitan. 2021;90(4):53-63. Russian. Olatunji LA, Oyeyipo IP, Micheal OS, Soladoye AO. Effect of dietary magnesium on glucose tolerance and plasma lipid during oral contraceptive administration in female rats. Afr J Med Med Sci. 2008 Jun;37(2):135-9. PMID: 18939396. Olatunbosun DA, Adeniyi FA, Adadevoh BK. Effect of oral contraceptives on Serum magnesium levels. Int J Fertil. 1974;19(4):224-6. PMID: 4376539.

Recommended Replacement

Magnesium Citrate100mg

Related Health Impacts

  • Irregular Heartbeat & Heart Risks

    Low or depleted magnesium levels are associated with a higher likelihood of several cardiovascular problems, including arrhythmias, where people with low magnesium have been shown to have 2–4 times higher odds of these rhythm disturbances compared with those with normal levels. Low magnesium is also linked to worsening coronary artery disease, progression of heart failure, and development or aggravation of hypertension, driven by disrupted cardiac electrical stability, vascular function, and electrolyte balance. Even mild magnesium depletion may contribute to higher blood pressure over time, adding to the overall cardiovascular burden, especially in individuals with existing heart disease or multiple risk factors.

Supplement Recommendation

Magnesium (as Magnesium Citrate) by Pure Encapsulations150 mg

Other Nutrients Affected by Leena

Next Steps
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