Create an account to receive alerts on new research
SaveShareAsk AI
Kariva

Kariva & Vitamin C

Depletes Vitamin C. This medication is commonly used for Contraception

Why Kariva affects Vitamin C

Studies suggest that women using oral contraceptives might have lower levels of vitamin C within their white blood cells (leukocytes) and platelets. This depletion could be linked to reduced activity of antioxidant enzymes like glutathione peroxidase (GPx) and glutathione reductase (GR) in the blood. These enzymes play a role in protecting cells from damage. Research also shows that supplementing with vitamin C, alongside vitamin E, can significantly increase the activity of these antioxidant enzymes in women taking OCs. This suggests that vitamin C supplementation might be beneficial for women on birth control pills.

Clinical Evidence

Zal F, Mostafavi-Pour Z, Amini F, Heidari A. Effect of vitamin E and C supplements on lipid peroxidation and GSH-dependent antioxidant enzyme status in the blood of women consuming oral contraceptives. Contraception. 2012 Jul;86(1):62-6. Palmery M, Saraceno A, Vaiarelli A, Carlomagno G. Oral contraceptives and changes in nutritional requirements. Eur Rev Med Pharmacol Sci. 2013 Jul;17(13):1804-13. PMID: 23852908. Shikh EV, Makhova AA, Chemeris AV, Tormyshov IA. [Iatrogenic deficits of micronutrients]. Vopr Pitan. 2021;90(4):53-63. Russian. Thorp VJ. Effect of oral contraceptive agents on vitamin and mineral requirements. J Am Diet Assoc. 1980 Jun;76(6):581-4. PMID: 7400487.

Recommended Replacement

Vitamin C Ascorbic Acid125 mg

Related Health Impacts

  • Eye Bleeding & Vision Issues

    Vitamin C deficiency weakens collagen in capillary and vascular walls, so severe scurvy can present with ocular hemorrhages in the conjunctiva and retina that threaten vision if not treated. Case reports and small series describe retinal hemorrhages, flame‑shaped hemorrhages, and even retrobulbar bleeding compressing the optic nerve, which can lead to optic neuropathy and visual loss in advanced cases. The encouraging point is that, when vitamin C deficiency is recognized early and promptly repleted, many ocular hemorrhages and visual symptoms can partially or fully resolve, making it critical to consider vitamin C status in patients with otherwise unexplained ocular bleeding and visual complaints.

Supplement Recommendation

Vitamin C (Ascorbic Acid) by Pure Encapsulations200 mcg

Other Nutrients Affected by Kariva

Next Steps
Save this report and share it with your healthcare provider or a family member
Ask our expert AI assistant additional questions related to Kariva.