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Hydrochlorothiazide + Olmesartan

Nutrients Depleted by Hydrochlorothiazide + Olmesartan

Prolonged use of Hydrochlorothiazide + Olmesartan can impact 5 essential nutrients. This medication is commonly used for Hypertension.

  • Magnesium

    This drug is a comprehensive combination of a thiazide diuretic and angiotensin receptor blocker. Taking thiazide diuretics long-term can increase magnesium loss. Monitoring magnesium levels and considering supplementation might be necessary when taking thiazide diuretics for an extended period of time.

    Replace with Magnesium Citrate (50 mg)

  • Zinc

    This drug is a comprehensive combination of a thiazide diuretic and angiotensin receptor blocker. Thiazide diuretics, a common medication for high blood pressure, can increase how much zinc your body gets rid of through urine. It's advisable to monitor your blood zinc levels while taking these medications and consider zinc supplementation. Studies have shown that treatment with medications like Angiotensin Receptor Blockers (ARBs) can lead to zincuria, which is increased urinary excretion of zinc. This increased excretion may potentially lead to zinc deficiency in some individuals and therefore supplementation should be considered.

    Replace with Zinc (as zinc bisglycinate and (TRAACS™) (12.5 mg)

  • Folic Acid

    This drug is a comprehensive combination of a thiazide diuretic and angiotensin receptor blocker. Studies indicate thiazide diuretics may act like folate antagonists, potentially leading to folate deficiency. Research suggests long-term use (over six months) can significantly decrease blood folate levels while increasing homocysteine, a potentially harmful amino acid linked to vascular disease. Folate supplementation should be considered while on thiazide diuretics.

    Replace with Folate (.2mg as L-5-Methylfolate) (0.34 DFE)

  • Potassium

    This drug is a comprehensive combination of a thiazide diuretic and angiotensin receptor blocker. Thiazide diuretics can cause potassium to leave your cells. These medications work by making your kidneys flush out water and sodium, but unfortunately, potassium gets swept along too. This raises the risk of a moderate or severe potassium deficiency, called hypokalemia and potassium supplementation should be considered.

    Replace with Potassium (as citrate and gluconate) (99 mg)

  • CoQ10

    This drug is a comprehensive combination of a thiazide diuretic and angiotensin receptor blocker. Thiazide diuretics may decrease the effectiveness of enzymes in your heart that rely on CoQ10 for function. This nutrient is essential for cellular energy production. Patients taking these medications might consider CoQ10 supplementation to address potential deficiencies.

    Replace with 50% Ubiquinone and 50% Ubiquinol (50 mg)

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