Suppresses absorption of Chromium. This medication is commonly used for Depression
Research suggests the trace mineral chromium may offer some benefits for people experiencing depression, particularly those with atypical depression. Atypical depression is characterized by symptoms like increased appetite, carbohydrate cravings, and weight gain, alongside feelings of sadness and low mood. Studies show chromium supplementation might improve these specific symptoms in people with atypical depression who also have strong carbohydrate cravings. The potential explanation lies in chromium's possible effects on insulin utilization and brain chemicals like serotonin and norepinephrine, both of which are involved in mood regulation. Supplementation with chromium is suggested to support mood and help protect against depression.
Docherty JP, Sack DA, Roffman M, Finch M, Komorowski JR. A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving. J Psychiatr Pract. 2005 Sep;11(5):302-14. Davidson JR, Abraham K, Connor KM, McLeod MN. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biol Psychiatry. 2003 Feb 1;53(3):261-4. Malcolm N. McLeod, Robert N. Golden, Chromium treatment of depression, International Journal of Neuropsychopharmacology, Volume 3, Issue 4, December 2000, Pages 311–314,
Chromium Picolinate — 200 mcg
Chromium is a cofactor for insulin signaling complexes; inadequate chromium status has been associated in some studies with impaired glucose tolerance and worsened glycemic control, though human data are mixed.
Low chromium status has been linked observationally to dyslipidemia and features of metabolic syndrome, although causality and clinical significance remain debated.
Chromium Picolinate by Pure Encapsulations — 200 mcg