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Eohilia
Depletes
Prolonged use of Eohilia can impact 3 essential nutrients.
Selenium
Corticosteroids can increase the urinary loss of selenium elevating the risk for deficient levels. Selenium is a mineral that acts as an antioxidant, helping protect cells from damage. Studies have shown that rheumatoid arthritis patients taking high doses of corticosteroids tend to have lower selenium levels. This is concerning because low selenium intake is linked to osteoporosis, and selenium has been shown to play a role in bone protection in animal models of corticosteroid-induced osteoporosis. Supplementation with selenium should be considered during long term corticosteroid therapy.
Replace with Selenium (as Se-Methyl L-Selenocysteine, L-selenomethionine (yeast free), sodium selenite) (150 mcg)
Research: Luo Y, Xiang Y, Lu B, Tan X, Li Y, Mao H, Huang Q. Association between dietary selenium intake and the prevalence of...
Calcium
Corticosteroids can lower calcium levels in the body. This is a double threat to bone health because corticosteroids themselves can weaken bones. Calcium is essential for strong bones, and a study showed that supplementing with both calcium and vitamin D3 helped prevent bone loss in people with rheumatoid arthritis taking corticosteroids. Supplementation with calcium should be considered during long term corticosteroid therapy.
Replace with Calcium Citrate (75 mg)
Research: Homik J, Suarez-Almazor ME, Shea B, Cranney A, Wells G, Tugwell P. Calcium and vitamin D for corticosteroid-induced...
Vitamin D
Research suggests corticosteroids can lower vitamin D levels in the body by increasing its breakdown. This is a concern because vitamin D plays a crucial role in bone health and the immune system, and corticosteroids themselves can weaken bones. A study found that calcium and vitamin D3 supplements helped prevent bone loss in the lower back (lumbar spine) and hip (trochanter) for people with rheumatoid arthritis who were on low-dose corticosteroids. Evidence suggests vitamin D may work synergistically together with corticosteroids to improve asthma treatment by boosting the effectiveness of corticosteroids or by overcoming resistance to these medications in some patients.
Replace with Vitamin D3 (Cholcalciferol) (1000 IU) (25 mcg)
Research: Banerjee A, Damera G, Bhandare R, Gu S, Lopez-Boado Y, Panettieri R Jr, Tliba O. Vitamin D and glucocorticoids...
Health Impact
Eohilia-induced nutrient depletion can lead to a range of health problems
Possible Higher Cancer Risk
For someone wondering whether low selenium is “just a lab number,” very low selenium status has been linked in epidemiologic research to a higher risk of cancer over time, especially when blood levels fall below roughly 70 µg/L. In one nested case‑control study, women with serum selenium at or below this level had more than double the overall cancer risk compared with those in the 80–90 µg/L range (odds ratio about 2.6, with confidence intervals that did not cross 1), which fits broader data showing higher cancer rates in clearly deficient populations. At the same time, experts still debate the exact causal role and ideal target range, so the practical takeaway is that identifying and correcting frank selenium deficiency—rather than pushing to very high intakes—may be a sensible strategy for people at risk who want to support long‑term cellular and immune health.
Research: Narod SA, Huzarski T, Jakubowska A, Gronwald J, Cybulski C, Oszurek O, Dębniak T, Jaworska-Bieniek K, Lener M, Białkowska K,...
High Blood Pressure & Heart Risk
Across the lifespan, chronically low calcium intake has been linked to higher blood pressure, in part because calcium plays a key role in vascular smooth‑muscle contraction, sodium handling, and endothelial function. Large epidemiologic studies and randomized trials suggest that individuals with higher dietary calcium intake tend to have modestly lower systolic and diastolic blood pressures and may experience a small but meaningful reduction in risk of stroke and other cardiovascular events. The practical takeaway is that maintaining adequate daily calcium, alongside blood pressure control, exercise, and a heart‑healthy diet, may be an underutilized strategy to support vascular health and reduce long‑term cardiovascular risk.
Research: Kim MH, Bu SY, Choi MK. Daily calcium intake and its relation to blood pressure, blood lipids, and oxidative stress...
Weakened Heart Muscle
Selenium deficiency is a well‑established cause of dilated cardiomyopathy and heart failure in low‑selenium regions, classically described as Keshan disease. In these endemic low‑selenium areas, large supplementation trials with sodium selenite significantly reduced the incidence of Keshan disease, providing strong evidence that inadequate selenium intake is a major causal factor rather than a mere association. Modern case reports in patients on long‑term parenteral nutrition, after bariatric surgery, or on highly restrictive elemental diets describe severe, sometimes rapidly progressive heart failure that improves with selenium repletion, underscoring that selenium‑deficiency cardiomyopathy remains a relevant, treatable diagnosis in contemporary clinical practice.
Research: Yusuf SW, Rehman Q, Casscells W. Cardiomyopathy in association with selenium deficiency: a case report. JPEN J Parenter...
Weak Bones & Fractures
In adults, chronically low calcium intake can quietly erode skeletal integrity, contributing to osteopenia, osteoporosis, and a higher risk of low‑trauma fractures over time. In children, inadequate calcium (often alongside vitamin D deficiency) impairs normal mineralization of the growing skeleton, leading to rickets with bone pain, deformities, and delayed growth, while in adults the same process manifests as osteomalacia with diffuse bone pain and muscle weakness rather than early fractures. The encouraging reality is that optimizing daily calcium intake, paired with sufficient vitamin D, protein, and weight‑bearing activity, has been shown to improve bone mineral density and meaningfully reduce fracture risk in at‑risk populations.
Research: Bischoff-Ferrari HA, Rees JR, Grau MV, Barry E, Gui J, Baron JA. Effect of calcium supplementation on fracture risk: a...
Airway Spasms & Breathing Issues
In some patients, significant calcium deficiency leading to hypocalcemia can present with acute respiratory manifestations such as laryngospasm and bronchospasm, often in the context of generalized neuromuscular irritability and tetany. Case reports describe episodes of stridor, tightness in the chest, and even acute respiratory distress that improve as ionized calcium levels are corrected. The key clinical implication is that, when otherwise unexplained laryngospasm or bronchospasm occurs alongside perioral numbness, carpopedal spasm, or muscle cramps, prompt evaluation and correction of calcium deficiency can be lifesaving and help prevent recurrent respiratory compromise.
Research: Kennedy J, Pérusse L, Drapeau V, Tremblay A. Cardiorespiratory Fitness in Low Calcium Consumers: Potential Impact of Calcium...
Memory Decline in Older Adults
For an older adult who is feeling “foggy,” forgetful, or mentally slower than they used to be, low selenium status has been linked in several studies to poorer cognitive performance and faster decline compared with peers who have adequate levels. A 2024 trial found that increasing selenium intake improved cognitive test scores only in older adults who already had low baseline cognition, but not in those whose cognition started out normal, suggesting that correcting true deficiency may specifically help a vulnerable subgroup rather than acting as a universal brain booster. Practically, this means that in older people with both low selenium and noticeable cognitive change, assessing status and considering careful selenium repletion may be a reasonable, targeted strategy to support brain function alongside other dementia‑prevention and brain‑health approaches.
Research: Akbaraly TN, Hininger-Favier I, Carrière I, Arnaud J, Gourlet V, Roussel AM, Berr C. Plasma selenium over time and cognitive...
Thyroid Problems
For someone living with fatigue, hair loss, weight changes, or that “wired‑but‑tired” feeling of thyroid trouble, low selenium status can quietly worsen thyroid function because selenium‑dependent enzymes help both activate thyroid hormone and protect thyroid tissue from the oxidative stress of making it. Clinical trials in autoimmune thyroiditis using about 200 µg per day of selenium have shown meaningful reductions in thyroid peroxidase (TPO) antibody levels and, in some studies, better thyroid ultrasound findings and improved day‑to‑day well‑being, even if the impact on long‑term medication requirements is less consistent. Taken together, this suggests that true selenium deficiency can both aggravate hypothyroid symptoms and dial up autoimmune activity in the thyroid, making selenium testing and thoughtfully dosed supplementation a smart conversation point for people with Hashimoto’s or other chronic thyroid disorders who do not feel fully optimized.
Research: Kobayashi R, Hasegawa M, Kawaguchi C, Ishikawa N, Tomiwa K, Shima M, Nogami K. Thyroid function in patients with selenium...
Side Effects
Common side effects of Eohilia, some of which may be related to nutrient depletion
Review
Eohilia, used to treat inflammation, may cause side effects such as nausea, dizziness, and headaches. Some patients might also experience gastrointestinal issues like stomach pain or diarrhea. It's important to consult a healthcare provider for a comprehensive list of potential side effects and personalized medical advice.
Get Support
We've curated a list of vetted, recommended individual nutrient third-party supplements.
Shop Third-Party Supplements
Calcium Citrate
by Solaray
The Calcium supplement by Solaray is designed to support bone health and overall wellness by providing a high-quality, bioavailable form of calcium.
Strength: 200mg
Buy now
Calcium Citrate
Expert Research
Recommended
Recommended
Selenium (as L-selenomethionine)
by Pure Encapsulations
The Selenium supplement by Pure Encapsulations is a dietary supplement designed to support antioxidant defenses and overall health by providing a bioavailable form of selenium, an essential trace mineral.
Strength: 200 mcg
Buy now
Selenium (as L-selenomethionine)
Expert Research
Recommended
Recommended
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