Prolonged use of Endep can impact 3 essential nutrients. This medication is commonly used for Depression.
Coenzyme Q10 (CoQ10), also known as ubiquinone, is a vital nutrient found in nearly every cell in the body. CoQ10 plays a key role in cellular energy production, acting within the mitochondria, the powerhouses of our cells. Research suggests a connection between mitochondrial dysfunction and depression, and this dysfunction might even be worsened by some antidepressant medications like amitriptyline. It found that tricyclic amines such as amitriptyline treatment in human cells decreased the levels of CoQ10. Supplementation with COQ10 could help improve overall cellular health and potentially alleviate symptoms associated with mitochondrial dysfunction in depression.
Replace with COQ 10 (as Ubiquinone) (50 mg)
Research on the connection between vitamin B3 (niacin) and depression is growing. Studies suggest that people who met the recommended dietary allowance (RDA) for niacin had a significantly lower risk of depression compared to those with lower intake. Vitamin B3 plays a role in converting food into energy, which is essential for brain function and overall well-being. Deficiencies can lead to fatigue and low mood. Some research suggests vitamin B3 might be involved in the production of neurotransmitters like serotonin, which plays a role in mood regulation. Deficiencies in some neurotransmitters are linked to depression. Supplementation with vitamin B3 may help support mood and protect against depression.
Replace with Vitamin B3 (50% Niacin and 50% Niacinamide) (20 mg)
Vitamin B2 (Riboflavin) may play a role in mood regulation, particularly in older adults. Research has found an association between higher dietary intake of vitamin B2 and lower scores on a depression scale (Geriatric Depression Scale) in elderly individuals. Vitamin B2 converts food into energy, which is essential for all bodily functions, including brain function. Deficiencies can lead to fatigue and low mood. It is also involved in the production of neurotransmitters, the chemical messengers in the brain that influence mood. Deficiencies in some neurotransmitters are linked to depression. Supplementation with vitamin B2 may help support mood and protect against depression.
Replace with Vitamin B2 Riboflavin (10 mg)