Create an account to receive alerts on new research
SaveShareAsk AI
Aspirin

Aspirin & Vitamin B12

Suppresses absorption of Vitamin B12. This medication is commonly used for Pain Management

Why Aspirin affects Vitamin B12

Research found that individuals hospitalized with heart disease and a history of aspirin use were nearly twice as likely to have low or borderline vitamin B12 levels compared to non-aspirin users. While this doesn't definitively prove aspirin causes B12 deficiency, it raises a potential link. Aspirin can irritate the stomach lining in some individuals. This is concerning because the stomach plays a crucial role in vitamin B12 absorption by producing hydrochloric acid and intrinsic factor. Both are essential for proper B12 uptake.

Clinical Evidence

van Oijen MG, Laheij RJ, Peters WH, Jansen JB, Verheugt FW; BACH study. Association of aspirin use with vitamin B12 deficiency (results of the BACH study). Am J Cardiol. 2004 Oct 1;94(7):975-7. Wu, Y., Smith, A.D., Refsum, H. et al. Effectiveness of B Vitamins and Their Interactions with Aspirin in Improving Cognitive Functioning in Older People with Mild Cognitive Impairment: Pooled Post-Hoc Analyses of Two Randomized Trials. J Nutr Health Aging 25, 1154–1160 (2021).

Recommended Replacement

Vitamin B12 Methylcobalamin0.2 mg

Supplement Recommendation

Vitamin B12 Methylcobalamin by Pure Encapsulations0.2 mg

Other Nutrients Affected by Aspirin

Next Steps
Save this report and share it with your healthcare provider or a family member
Ask our expert AI assistant additional questions related to Aspirin.