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Alesse

Alesse & Tyrosine

Suppresses absorption of Tyrosine. This medication is commonly used for Contraception

Why Alesse affects Tyrosine

Women using oral contraceptives (OCs) may experience mood changes, including depression. Research suggests a potential link between these emotional shifts and a decrease in brain levels of the neurotransmitter norepinephrine (noradrenaline). This decrease could be related to reduced availability of its precursor molecule, tyrosine, in the brain. Studies have shown a significant decline in tyrosine levels in women on OCs. One study found that the area under the curve (AUC) in plasma for tyrosine in OC users were 43% of control levels. Tyrosine supplementation could potentially help regulate mood and improve emotional well-being while taking OCs.

Clinical Evidence

Møller, S.E., Maach-Møller, B., Olesen, M., Madsen, B.K., Madsen, P., & Fjalland, B. (1995). Tyrosine metabolism in users of oral contraceptives. Life sciences, 56 9, 687-95 .P.G. Masse, et al. Testing the Tyrosine/Catecholamine Hypothesis of Oral Contraceptive-Induced Psychological Side-Effects: A Controlled Study on Triphasil. Ann Nutr Metab (2001) 45 (3): 102–109. Svend E. Møller. Effect of Oral Contraceptives on Tryptophan and Tyrosine Availability: Evidence for a Possible Contribution to Mental Depression. Neuropsychobiology (1981) 7 (4): 192–200.

Recommended Replacement

L-Tyrosine200 mg

Supplement Recommendation

L-Tyrosine by Pure Encapsulations500 mg

Other Nutrients Affected by Alesse

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